Maturation of Skin Serum vertebrate oocytes into haploid gametes relies on two consecutive meioses without intervening DNA replication.The temporal sequence of cellular transitions driving eggs from G2 arrest to meiosis I (MI) and then to meiosis II (MII) is controlled by the interplay between cyclin-dependent and mitogen-activated protein kinases.
Analyzing complex problem domains is not easy.Simulation tools support decision makers to find the best policies.Model-based system development is an approach where a model of the application domain is the central driving force when designing simulation tools.State-of-the-art techniques however still require both expert knowledge of the application
Abstract Background Soil salinization is a worldwide problem that is intensifying because of the effects of climate change.An effective method for the reclamation of salt-affected soils involves initiating plant succession using fast growing, nitrogen fixing actinorhizal trees MODUCARE such as the Casuarina.The salt tolerance of Casuarina is enhanc
Recombinant adeno-associated virus (rAAV) platforms hold promise for in vivo gene therapy but are undermined by the undesirable transduction of antigen presenting cells (APCs), which in turn can trigger host immunity towards rAAV-expressed transgene products.In light of recent adverse events in patients receiving high systemic AAV vector doses that
Background.Retinoblastoma (Rb) cases with atypical clinical manifestations, which lead to error diagnosis and inadequate treatment, have become more frequent over the last years.Purpose.To describe and to analyze a clinical picture, diagnostics, and treatment of vitrectomy performed in an eye with unsuspected Auto Feed Rb resulted in pre-operationa